Zika virus infection triggers caspase cleavage of STAT1
ABSTRACT Zika virus (ZIKV) is an important pathogen that causes Guillain-Barre syndrome in adults and congenital Zika syndrome in newborns.Interferon (IFN) triggers intracellular antiviral signaling through two essential mediators STAT1 and STAT2, which are critical for host innate antiviral immunity.ZIKV has been reported to antagonize host IFN si